Discussions on the origins and nature of pain have been taking since ancient times. In Greek mythology the goddess of revenge, Poine, was sent to punish the mortal fools who had angered the gods and the word ‘pain’ comes from the Latin "poena" meaning a penalty.
Significant progress in elucidating the mechanisms involved in the development of pain has been made in recent years, due to the use of advanced genetic, molecular, electrophysiological, imaging and behavioural techniques.
Acute pain is part of an early warning system instructing the nervous system to minimize detected physical harm and to avoid tissue damage from environmental stimuli.
Nonsteroidal anti-inflammatory drugs are the cornerstone of the acute inflammatory pain management.